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If we revisit our original equation for muscle mass, it's plain to see that increasing synthesis and decreasing breakdown will equate to muscle gain or maintenance. Have Better Workouts
Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. 2010 May;24(5):1215-22. doi: 10.1519/JSC.0b013e3181cb28e0. PMID: 20386132. Van de Worp W, et al. (2020). Nutritional interventions in cancer cachexia: Evidence and perspectives from experimental models. Several older studies have shown that taking BCAA supplements may offer protection against liver cancer in people with liver cirrhosis ( 31, 32).BCAAs may offer health benefits for people with cirrhosis, a chronic disease in which the liver does not function properly. Mero A. Leucine supplementation and intensive training. Sports Med. 1999 Jun;27(6):347-58. doi: 10.2165/00007256-199927060-00001. PMID: 10418071. However, effects may vary based on your gender or the total protein content of your diet ( 19, 24). Summary
According to a 2019 review, evidence suggests that BCAAs stimulate muscle protein synthesis after exercise but that the other essential amino acids are also important for this process. In your brain, tryptophan is converted to serotonin, a brain chemical that is thought to contribute to the development of fatigue during exercise ( 14, 15). What’s more, Thorne was given an A rating from the Therapeutic Goods Association (TGA), an Australian regulatory agency that sets strict requirements for supplement manufacturing. Before adding a BCAA supplement to your lineup, you may want to consider a few big factors. As BCAAs are pretty versatile, you may want to consider ingredients, dosages, formulation, price, calories, and the necessity of BCAAs before making your selection. We detail each of these more below. Ingredient ListCórdova-Martínez A, et al. (2021). Effect of glutamine supplementation on muscular damage biomarkers in professional basketball players. The authors of a 2019 review observed that BCAA supplementation reduced delayed onset muscle soreness after exercise.