Natures Aid Odourless Garlic Pearls, 120 Softgel Capsules (One-a-Day, to Help Maintain a Healthy Heart and Blood Circulation, Made in the UK)

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Other compounds that may play a role in garlic’s health benefits include diallyl disulfide and s-allyl cysteine. It is believed that the builders of the Egyptian pyramids were plied with garlic to keep their strength up. Some drugs that may interact with this product include: protease inhibitors (e.g., indinavir, saquinavir), non-nucleoside reverse transcriptase inhibitors (NNRTIs such as nevirapine, efavirenz), isoniazid, medications/herbal products that may increase your risk of bleeding (e.g., "blood thinners" such as warfarin and heparin, anti-platelet drugs such as clopidogrel, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen, herbals such as danshen/ginger/gingko).

Doma K, Devantier-Thomas B, Gahreman D, Connor J. Selected root plant supplementation reduces indices of exercise-induced muscle damage: s systematic review and meta-analysis. Int J Vitam Nutr Res. 2020;1-21. doi:10.1024/0300-9831/a000689 We all know a garlic lover or two in our lives – you know, the ones who double the necessary cloves for every recipe!To compensate, the process also creates a high concentration of an antioxidant called S-Allycysteine (SAC), which makes the remaining allicin more bioavailable. Garlic oil could be an effective agent or food supplement in reducing the toxicity of tributyltin ( Reference Liu and Xu 25 ). Allicin-mediated lipoperoxide production in fungal plasma membranes is the cause of the enhancement in the cellular uptake of polymyxin B as well as its action against the vacuole ( Reference Ogita, Nagao and Fujita 26 ). Supplementation of garlic oil at 5 mg/kg body weight has been shown to have an anticoagulation effect in an animal study ( Reference Chan, Yin and Chao 27 ).

Garlic Pearls Capsule helps to maintain blood sugar levels and triglyceride levels. It helps in managing high blood pressure and may prevent against the hardening of the arteries. It also boosts immunity and digestive health. Regular consumption helps in maintaining a healthy heart and digestion. A very serious allergic reaction to this product is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Whole garlic and aqueous garlic extract exhibit direct antioxidant effects and enhance the serum levels of two antioxidant enzymes: catalase and glutathione peroxidase ( Reference Kumaraguruparan, Chandra Mohan and Abraham 28 ). Garlic extract and allicin efficiently scavenged exogenously generated hydroxyl radicals in a dose-dependent fashion ( Reference Prasad, Haxdal and Yu 29 ). Other garlic constituents, such as SAC, also demonstrated significant antioxidant effects in vitro ( Reference Imai, Ide and Nagae 30 ). The sulfur compounds found in fresh garlic appear to be nearly 1000 times more potent as antioxidants than those found in aged garlic extract ( Reference Melaleb 31 ). However, other scientists have reported that the cholesterol reduction in the blood may not be significant. 7Borlinghaus J, Albrecht F, Gruhlke MC, Nwachukwu ID, Slusarenko AJ. Allicin: chemistry and biological properties. Molecules. 2014;19(8):12591-12618. Published 2014 Aug 19. doi:10.3390/molecules190812591 Shi X, et al. (2019). Garlic consumption and all-cause mortality among Chinese oldest-old individuals: A population-based cohort study.

Use of Natural Products by Children : What the Science Says. NCCIH. https://www.nccih.nih.gov/health/providers/digest/use-of-natural-products-by-children-science There is no reference nutrient intake (RNI) for garlic. However, it’s safe to consume atnormal levels found in your food. 14 Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.The smell of Garlic Pearls may be noticeable on the breath and skin. If this is bothersome, use an enteric-coated Garlic Pearls product. Dehgani S, et al. (2018). The effect of a garlic supplement on the pro-inflammatory adipocytokines, resistin and tumor necrosis factor-alpha, and on pain severity, in overweight or obese women with knee osteoarthritis. H-C Ou et al., Journal of Agricultural and Food Chemistry: "Cardiac Contractile Dysfunction and Apoptosis in Streptozotocin-Induced Diabetic Rats Are Ameliorated by Garlic Oil Supplementation." Zarezadeh M, et al. (2017). Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms.

This also helps support heart health and the maintenance of good cholesterol levels. The dosage here is slightly higher, with 3.6 mg of allicin per capsule. Again though, one capsule can be taken per day, with food. Shanmugam KR, Shanmugam B, Subbaiah GV, Ravi S, Reddy KS. Medicinal Plants and Bioactive Compounds for Diabetes Management: Important Advances in Drug Discovery. Curr Pharm Des. 2021;27(6):763-774. doi:10.2174/1381612826666200928160357 One of the key advantages of Garlic Pearls is their ability to fortify the immune system. By strengthening your body's natural defences, these capsules help protect against common illnesses and promote overall wellness. And that's not all! Garlic Pearls also work wonders for cardiovascular health. They have been shown to improve blood sugar and cholesterol levels, reducing the risk of heart disease and maintaining optimal cardiovascular function. Garlic oil has also been found to be protective against cardiomyopathy, a type of chronic heart disease that is the leading cause of death among diabetes patients. When diabetic mice were fed garlic oil, they developed more changes associated with cardiac protection than diabetic mice in the control group. Further research is needed to understand the effects on humans.

Dosage: How much garlic is safe to take?

H. Kim et al., International Journal of Cancer: "Garlic intake and gastric cancer risk: Results from two large prospective US cohort studies." Haghi A, Azimi H, Rahimi R. A Comprehensive Review on Pharmacotherapeutics of Three Phytochemicals, Curcumin, Quercetin, and Allicin, in the Treatment of Gastric Cancer. J Gastrointest Cancer. 2017;48(4):314-320. doi:10.1007/s12029-017-9997-7 Sun Y-E, et al. (2018). Anti-hyperlipidemia of garlic by reducing the level of total cholesterol and low-density lipoprotein. Ried K, Toben C, Fakler P. Effect of garlic on serum lipids: an updated meta-analysis. Nutr Rev. 2013;71(5):282-99. doi: 10.1111/nure.12012.