CoQ10 200mg - 120 Vegan Capsules of High Strength Co Enzyme Q10 (4 Months Supply) - 100% Pure and Naturally Fermented Ubiquinone Coenzyme - No Synthetic Additives - Made in The UK by Nutravita

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Johansson, P., et al. (2015). Improved health-related quality of life, and more days out of hospital with supplementation with selenium and coenzyme Q10 combined. Results from a double blind, placebo-controlled prospective study [Abstract]. CoQ10 might help treat specific heart conditions, such as congestive heart failure and high blood pressure, particularly among older individuals.

Zhang, Y., et al. (2018). Ubiquinol is superior to ubiquinone to enhance Coenzyme Q10 status in older men [Abstract]. When applied to the skin: Coenzyme Q10 is LIKELY SAFE for most adults when applied directly to the gums. Pregnancy and breast-feeding: Coenzyme Q10 is POSSIBLY SAFE when taken by mouth appropriately during pregnancy. Coenzyme Q10 has been used safely when taken twice daily starting at 20 weeks until delivery. Not enough is known about the use of coenzyme Q10 during breast-feeding. Stay on the safe side and avoid use.

Research suggests that mitochondrial dysfunction can contribute to age-related neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. These diseases are associated with free radical damage. Alahmar AT. The impact of two doses of coenzyme Q10 on semen parameters and antioxidant status in men with idiopathic oligoasthenoteratozoospermia. Clin Exp Reprod Med. 2019 Sep;46(3):112-118. doi:10.5653/cerm.2019.00136 A 6-week study in 100 German athletes found that those who supplemented with 300 mg of CoQ10 daily experienced significant improvements in physical performance — measured as power output — compared to a placebo group ( 36). Lei L & Liu Y. (2017). Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials.

A pregnancy complication marked by high blood pressure and protein in the urine (pre-eclampsia). Pre-eclampsia is a condition that some women develop during pregnancy. Some research shows that women who are at risk have a lower chance of developing the condition if they take coenzyme Q10 from week 20 of pregnancy until the baby is delivered. A 2018 meta-analysis reexamined five studies investigating the use of CoQ10 supplements for migraines. The meta-analysis concluded that CoQ10 is more effective than a placebo at reducing the duration of migraines. However, CoQ10 did not appear to affect migraine severity or frequency. Protecting against age-related diseases The third-party certifications we can trust are ConsumerLab.com, NSF, and USP. However, these certifications are difficult to obtain and/or expensive for manufacturers, so many companies choose not to get their products tested by one of these three organizations. In one 2018 pilot study, ten children with cardiac muscle dysfunction received 110–700 mg of liquid ubiquinol per day. At weeks 12 and 24 of treatment, the children had significantly higher CoQ10 plasma levels and improved heart function. Reducing muscle pain from statin use The participants who took the CoQ10 supplements had significantly reduced statin-related muscle pain. Those who received the placebo reported no change in muscle pain.

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Kidney failure. Some early research suggests that taking coenzyme Q10 improves kidney function in people with kidney failure. But it might not be helpful in people with less severe kidney disease. Molyneux, S. L., Florkowski, C. M., George, P. M., Pilbrow, A. P., Frampton, C. M., Lever, M., & Richards, A. M. (2008, October). Coenzyme Q10: An independent predictor of mortality in chronic heart failure. Journal of the American College of Cardiology, 52(18), 1435–1441 CoQ10 protects cells against oxidative damage. It also plays a vital role in producing the body’s primary source of energy, ATP. CoQ10 could, therefore, provide a range of health benefits. Some examples include: Improving heart health The only downsides? It uses soybean oil as a solvent, and relies on gelatin capsules with a few more additives than we’d like to see. 9. NutriONN Extra Strength CoQ10

Gholnari T, et al. (2018). The effects of Coenzyme Q10 supplementation on glucose metabolism, lipid profiles, inflammation, and oxidative stress in patients with diabetic nephropathy: A randomized, double-blind, placebo-controlled trial. Other causes of CoQ10 depletion include statin medication use, heart disease, nutrient deficiencies, genetic mutations, oxidative stress and cancer ( 6). Heart failure and fluid build up in the body (congestive heart failure or CHF). Early research found that heart failure might be linked with low coenzyme Q10 levels. Some research shows that taking coenzyme Q10 might help reduce some symptoms of heart failure. Coenzyme Q10 might also reduce the chances of death or hospitalization related to heart failure. Oxidative damage is one of the main causes of both male and female infertility by negatively affecting sperm and egg quality ( 29, 30).Hearing loss. Some research suggests that taking coenzyme Q10 can improve hearing in some people with age-related hearing loss. But combining coenzyme Q10 with conventional steroid treatments doesn't improve hearing in people with sudden deafness. Also, it doesn't appear to improve hearing in people with noise-induced hearing loss. Coenzyme Q10 is an antioxidant. There is some concern that antioxidants might decrease the effectiveness of some medications used for cancers. But it is too soon to know if the interaction occurs. Some medications for cancer include busulfan, carboplatin, cisplatin, cyclophosphamide (Cytoxan), dacarbazine, thiotepa, and many others. Qu, H., Guo, M., Chai, H., Wang, W.-T., Gao, Z.-Y., & Shi, D.-Z. (2018, September 25). Effects of coenzyme Q10 on statin‐induced myopathy: An updated meta‐analysis of randomized controlled trials. Journal of the American Heart Association, 7(19)

High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). It's unclear if coenzyme Q10 reduces cholesterol levels. One study shows it might lower triglycerides and LDL (or "bad" cholesterol) by a small amount. Other studies show no benefit of taking coenzyme Q10 for lowering total cholesterol or LDL or increasing HDL (or "good" cholesterol) levels. It may take at least 3 months to see any benefit. Unlike other CoQ10 supplements, these softgels also contain 68 mg of vitamin E, 453% of the daily value. Vitamin E has been shown to be an important antioxidant to help lower oxidative stress associated with cardiovascular disease. Some animal studies have shown that taking CoQ10 with vitamin E helps reduce inflammation, and some human studies suggest vitamin E with CoQ10 may be beneficial for heart health in women with polycystic ovary syndrome (PCOS). Even though this is a high dose of vitamin E, it’s much lower than the tolerable upper limit of 1,000 mg for adults. CoQ10 also helps improve insulin resistance and regulate blood sugar levels in people with diabetes. American Academy of Neurology (2004, April 28). Study shows coenzyme Q10 may prevent migraine [Press Release]Doses of 300 mg per day appear to be most effective in boosting athletic performance in research studies ( 38). Summary Though 90–200 mg of CoQ10 per day is typically recommended, needs can vary depending on the person and condition being treated ( 8). Statin Medication Use Though these drugs are generally well tolerated, they can cause adverse side effects, such as serious muscle injury and liver damage.